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Tue 17 Mar 2026 • 12:52

**Long-Term Use of Omeprazole for Acid Reflux Linked to Increased Risk of Magnesium Deficiency and Bone Fractures**

**Long-Term Use of Omeprazole for Acid Reflux Linked to Increased Risk of Magnesium Deficiency and Bone Fractures**

**People Taking Omeprazole for Acid Reflux Warned About Two Issues with Long-Term Use**

People on omeprazole, a medicine used for acid reflux, have been informed about two possible problems that may arise from prolonged use. Experts warn that taking this medication for a year or longer can increase the risk of serious side effects.

According to the NHS, “The chance of getting serious side effects can be higher if you take omeprazole for a long time (a year or more).” This suggests that patients should consider the duration of their treatment carefully.

Common side effects linked to long-term omeprazole use include magnesium deficiency, which can lead to muscle spasms and heart issues. Additionally, there's a concern that extended use may raise the risk of bone fractures. People using this medication are encouraged to discuss their treatment plans with their GP, especially if they have concerns about these potential risks.

Patients should remain aware of these issues and contact their healthcare provider for guidance if they notice any adverse effects during their treatment.

This article is for general information only and is not a substitute for professional medical advice. Always speak to a GP or qualified health professional about your own health.